Osteonecrosis March 2008
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Osteonecrosis
You recall that this is the “jaw rot” after using Bisphosphonates such as Fosamax, Actonel, Boniva and the like. If it starts, the jaw rots completely away and you are left with some flaps of skin and similar flaps of gum where the teeth used to be.
We have now finished follow up on 12-15 patients using 50,000 IU of Vitamin D3 daily for 30 days or more and all the patients have undergone routine dental cleaning with no problems.
The people who were at risk for Osteonecrosis appear to have dodged the bullet and are going to be just fine. I always hope there will be no exceptions.
Labels: osteonecrosis, osteoporosis, vitamin D
posted by Dr. Joe @ 3/24/2008 06:16:00 AM
2 comments
2 Comments:
Are these people ONJ patients, or just patients who might be succeptable to ONJ? Does the Vitiamin D stop the progression of ONJ and/or promote the healing of ONJ?
Many thanks,
Grant
28 y/o cancer survivor, zometa-induced ONJ patient of maxilla
ONJ did not occur in the past before Bisphosphonates or in the presence of adequate vitamin D. Either way, our experience is that if you take 50,000 IU of Vitamin D3 for 30 to 40 days and then take D3 weekly in the same amount forever, the problem is over.
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