Why We Age
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Why we age (Text Summary)
The normal process of cells burning fuel leads to aging then to disease and disability. Metabolically we are all on fire.
It begins with the metabolic syndrome that proceeds along the three pronged path to cardiovascular disease, Alzheimer’s disease and diabetes.
Oxidative damage is the black beast of our decline and its accomplice is inflammation. First it is the oxidative stress and then the cytokines and free radicals spearhead the decline of the body called aging and disease.
These terms will be familiar to you as you will pull out all the antiaging therapies that are becoming familiar. Complicated to be sure but the understanding allows you and I to prioritize the attack on entire aging process. We have all learned these processes in pieces. Diabetes first, or perhaps cardiovascular disease but ever stalked by the specter of Alzheimer’s disease.
That’s why I start with l-arginine first since 75-85% of the aging process begins with cardiovascular disease. Proagi9 plus has many of the additional anti-aging components that makes the anti-aging attack so strong. Not just a frontal attack on aging but a splendid quenching of the firers that burn us out too soon, too unevenly. The Biology of Human Longevity. – Caleb Finch Academic, Amsterdam, 2007
Labels: l-arginine, metabolc syndrome
posted by Dr. Joe @ 3/17/2008 09:21:00 AM
4 comments
4 Comments:
Thanks Doctor Joe, Just a quick question. I have been on your l-arginine and vitamin D regimen for a couple of years now. (And I feel super I might as well add). You mentioned supplements for controlling the buildup of free radicals. I have been using the Juice Plus supplements recommended by Dr. H in NY for this purpose. Are you familiar with Juice Plus? Does the Mystica Acai you recommend perform similarly in free radical reduction or does it have additional benefits?
Dr. Joe great information for us all. Easy to understand and use with our family,friends and business contacts.
Jean&Joan
The Mystica has 5 times more oxidative force.
Thanks, Dr. Joe! I would say that Mystica probably has more like 10,000 times the antioxidant power. As explanation, I post below my discussion with the Juice Plus people. This is in reverse chrono order, so if you are interested, please start from the bottom. -Rich (I am identified as RB in the e-mails)
Date:
From: R RB
Subject: RE: Your Recent Juice Plus+R Transaction
To: Carlos Madero c.madero@nsai.com
Dr. Madero: Because you represent JP and because of the weakness of your response, I can now see why the entire marketing message of JP is so vague and misleading. I will take a moment to respond to your message, although I realize that I am probably wasting my time in attempting to educate you. You were unable to answer any of my challenges in either of my e-mails. My comments below are preceded by ***.
Carlos Madero c.madero@nsai.com wrote:
Good morning Mr. B,
I have requested our Customer Care group to verify your order is cancelled and to make the necessary arrangements for a refund.
I am not aware of any other similar product that has been scrutinized as closely as Juice Plus+®. If the internal review boards of places like M D Anderson in Texas authorize our product to be researched at their institution, they obviously think it is worth their time.
**** This is a meaningless and misleading statement. Show me evidence that "They obviously think it is work their time." Paid research protocols happen all the time. I can pay for research at a hospital, too, and they will do it instantly. What is the name of the study? Who heads it? In all reputable research, such things are reported as a matter of routine. I suspect that you are unable to do so.
There is also a project currently under way at Wake Forest University , funded by the National Cancer Institute of the National Institutes of Health. These are very reputable research institutions, and I can assure you they would not risk putting their good name together with a fly-by-night operation.
**** What is this project? What is the grant #? If it exists, you would tell me this. In fact, there is no such grant. I just visited the website for NIH, where all grants are listed. The NIH has NO GRANTS that mention Juice Plus in the protocol.
Juice Plus+® is a food product and its formula is proprietary. It is not common for food products to quantify each ingredient, especially when so much work has gone into developing the formula.
**** This statement is complete nonsense. ALL reputable vitamins and supplements quantify everything. Further, even if I were to ask Heinz what goes into their ketchup, they would answer me with quantities. The truth is that your product only has trivial and unstandardized quantities of vegetables.
Juice Plus+® is not designed to take the place of a balanced diet, and there is not any other food product that can do that either. NSA as a company fully supports the daily consumption of fruits and vegetables according to the guidelines of the National Institutes of Health and the World Health Organization (and everybody else on the planet).
*** Why are you making reference to these organizations? They have nothing to do with your organization. Are you trying to somehow associate your firm with the NIH and WHO?
This is very important for nutritionists and dietitians to understand, we are on their side. However, despite the unanimous advice of every health and nutrition expert in the world, the daily consumption of fruits and vegetables continues to decline throughout the world. That's where Juice Plus+® comes in - not as a substitute for fruits and veggies - but as a support system for this crucial food group.
**** Okay --- exactly what support? I have asked you repeatly for data or substantiation, but you refuse. This is the hallmark of a fraud.
Arginine is one of the twenty or so amino acids that compose most proteins. A person that eats the recommended 40 grams of protein a day gets about 3 – 4 grams of it.
**** You didn't answer my question or respond in an intelligent way. Isolated amino acid are not found in nature and you have added isolated arginine to your product.
The newsletter you mention is basically an opinion piece, is not peer reviewed and is not even published by Berkley .
**** You reveal yourself as a complete incompetent here. The Berkeley Wellness Letter is the official organ of The School of Public Health of the University of California at Berkeley.
You may notice it does not even have an author byline. While there is no such thing as a "perfect" study because there always ends up being something you might do differently, including even writing the text differently, in hindsight the company does have more than one study (10 in fact) on Juice Plus+® and twelve more in the works. I'm sure a determined critic can find fault with any of these, as well as any other article published in the same issue of the same journal.
**** NONE OF THE STUDIES REFERENCED ON YOUR WEBSITE SAY ANYTHING SIGNIFICANT ABOUT JUICE PLUS. FURTHER, IT IS COMPLETELY OBVIOUS THAT YOU ARE PAYING FOR THE STUDIES.
Their mention of O.J. Simpson shows how low they are willing to go to put Juice Plus+® in a bad light. It's clearly intended to slam Juice Plus+® and not be unbiased or fair, as any legitimate publication of this kind should be.
But as I said in my earlier note, I respect your decision, and I wish you well.
Best regards,
Carlos F. Madero, Ph.D.
Director, Technical Support
NSA Inc.
Voice Com 901.758.4522
MORE BELOW
From: R B
Sent: Thursday,
To: c.madero@nsai.com
Subject: RE: Your Recent Juice Plus+® Transaction
Dr. Madero:
In answer to your question, I am including below the e-mail that I sent your company on July 23, for which I received no response. I have also put a couple of notes in your e-mail to me, also below. I shall await your reply. RB
Dear Juice Plus: (July 23 letter)
1) I have carefully reviewed the material on your website, and have read the actual research papers cited (including the the article in the only reputable journal, Plotnick et al. Effect of supplemental phytonutrients on impairment of the flow-mediated brachial artery vasoactivity after a single high-fat meal. Journal of the American College of Cardiology 2003; 41 (10): 1744-1749, in which the authors observe that this small (n=15) study might show that JP may be about like taking a small amount of vitamin C or E, and they do not endorse JP).
2) I am disturbed about lack of quantitive data supplied on the content of the capsules (e.g., how much lipase? It is irresponsible to fail to list this information).
3) I see that several of the physicians on your website endorse fruits and vegetables, but NOT Juice Plus specifically. Yet, they are presented as endorsers.
4) The Vineyard product has a gram of arginine, an isolated amino acid that is completely unnatural.
5) I have read the critical reviews of your product in the UC Berkeley Wellness Letter.
It is clear to me that the intent is to distort the modest scientific basis of this product. Further, it is a matter of common sense to understand that a significant quantity of phytonutrients cannot be reduced to half a teaspoon of powder.
I have come to the conclusion that your product is a complete fraud.
I wish to return this product immediately, and I want a complete refund.
RB
juiceplus@nsai.com wrote:
Carlos Madero c.madero@nsai.com wrote:
Good morning RB,
I am sorry to hear of your decision to stop taking Juice Plus+®, I just want to say I respect your decision and I hope you can help me clarify some of the points you make so we make sure to correct any errors on our end;
1. Please help me understand what are the health claims you feel are deceptive. Same for the enzyme claims
RB Says: What enzymes are included and in what quantities?
2. The amounts the body needs of nutrients vary widely; I will give you some examples; the amount of vitamin B12 the body needs in a day is 0.006 mg a day. The recommended daily amount of Vitamin C in a day is 60 mg. The recommended daily amount of potassium is 3,500 mg, and the recommended daily amount of fiber is from 25,000 to 35,000 mg .
RB Says: You are quoting some RDAs, but why? It there some relationship to your product? You state no quantities of anything on your product.
Juice Plus+® is not a substitute or a replacement for any part of our diet, and these figures highlight that fact, we still have to procure as balanced a diet as we can.
4. You are correct, cellulose is non-digestible, and that is why it is considered part of the dietary fiber. The capsules are properly labeled, and fiber and cellulose are identified in the ingredients.
RB Says: Are the capsule contents 1% cellulose, 99% cellulose, or something in between, or do you even know the answer to this question?
Best regards,
Carlos F. Madero , Ph.D.
Director, Technical Support
NSA Inc.
Voice Com 901.758.4522
MORE BELOW
From: R B
Sent: Monday, August 28, 2006 8:37 AM
To: c.madero@nsai.com
Subject: Re: Your Recent Juice
***
Hi Steve: I have cancelled my orders for Juice Plus because I have
discovered that the health claims for the product are deceptive. I encourage you to read the published studies about Juice Plus, as I have, and you will see that the claimed benefits are either insignificant or nonexistent. This should be obvious when you see the size of the Juice Plus capsules -- it is simply not possible to include a significant quantity of phytochemicals in a few small capsules. Even pure grape proanthocyanin, for example, must be taken in quantities of hundreds of milligrams to be useful. The claims about "enzymes" are complete nonsense.
In addition, the capsules are not appropriately labeled as to their contents, and they contain an unspecified amount of indigestible and useless cellulose. -RB
customercare@ns.nsai.com wrote: 1731182*1 Our
records indicate that you recently suspended your Juice Plus+ order.
We have found that customers who discontinue Juice Plus+ often do so
because they simply forgot to take it every day and have too much
product
on hand. If this is the case and you are interested in receiving
another shipment of Juice Plus+ at some point, please let us know by
replying to this e-mail or by calling one of our Customer Care Specialists
at 1-800-347-6350, 8 a.m. - 5 p.m. Central Time, Monday - Friday. Well be
glad to assist you in making arrangements that suit your specific needs.
Thank you for your business. We hope to be able to serve you again soon.
Steve Williams Director Juice Plus+ Customer Care If you do not
wish to
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